It’s Time We Talked About
Testosterone and Women’s Health
Confused about hormones? You’re not alone.
Let’s make this make sense.
Hormone health is complex.
Women are often navigating it with incomplete information.
Testosterone is commonly associated with men’s health, yet it is produced in women throughout life and plays a role in how the body functions day to day. Despite this, women have been significantly underrepresented in testosterone research, and there is currently no FDA-approved testosterone therapy specifically for women.
At the same time, hormone and midlife clinicians have been prescribing compounded forms of testosterone for women for decades, based on clinical experience and emerging evidence. That disconnect, between real-world practice and formal research, leaves many women without clear guidance or consistent standards of care.
Our work focuses on clarifying this gap through science, clinical context, and lived experience.
WHY TESTOSTERONE MATTERS IN THE BODY
Testosterone is not a “male hormone.”
It’s a foundational hormone that supports multiple systems in the body.
In women, testosterone contributes to:

Physical energy and stamina
It plays a role in how the body produces and uses energy, influencing fatigue and physical resilience.

Muscle and bone integrity
Testosterone supports lean muscle mass and bone strength, which are critical for mobility and long-term health as women age.

Neurological and cognitive function
Androgens are involved in brain signaling and may influence focus, motivation, and mental clarity.
These effects don’t exist in isolation. Hormones work as a network, and changes in testosterone can influence how the body responds overall, especially during midlife.
KEY FACTS
Key Things to Know
Testosterone levels decline by about 50% by midlife
This change is gradual and often not routinely evaluated
Up to 80% of midlife women report persistent fatigue
Low energy is common, even without a clear diagnosis
Testosterone supports muscle strength, bone health, and physical vitality
Its role extends well beyond reproductive health

Understanding how hormones function is the first step toward clearer care and better advocacy.